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Glucose Homeostasis, Insulin Secretion, and Islet Phospholipids in Mice that Overexpress iPLA(2)β in Pancreatic β-Cells and in iPLA(2)β-Null Mice

Studies with genetically modified insulinoma cells suggest that Group VIA Phospholipase A(2) (iPLA(2)β) participates in amplifying glucose-induced insulin secretion. INS-1 insulinoma cells that overexpress iPLA(2)β, for example, exhibit amplified insulin secretory responses to glucose and cAMP-eleva...

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Bibliografske podrobnosti
Main Authors: Bao, Shunzhong, Jacobson, David A., Wohltmann, Mary, Bohrer, Alan, Jin, Wu, Philipson, Louis H., Turk, John
Format: Artigo
Jezik:Inglês
Izdano: 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268609/
https://ncbi.nlm.nih.gov/pubmed/17895289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00474.2007
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