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Glucose Homeostasis, Insulin Secretion, and Islet Phospholipids in Mice that Overexpress iPLA(2)β in Pancreatic β-Cells and in iPLA(2)β-Null Mice
Studies with genetically modified insulinoma cells suggest that Group VIA Phospholipase A(2) (iPLA(2)β) participates in amplifying glucose-induced insulin secretion. INS-1 insulinoma cells that overexpress iPLA(2)β, for example, exhibit amplified insulin secretory responses to glucose and cAMP-eleva...
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| Asıl Yazarlar: | , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2007
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2268609/ https://ncbi.nlm.nih.gov/pubmed/17895289 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00474.2007 |
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