Group VIA PLA(2) (iPLA(2)β) Is Activated Upstream of p38 Mitogen-activated Protein Kinase (MAPK) in Pancreatic Islet β-Cell Signaling

Group VIA phospholipase A(2) (iPLA(2)β) in pancreatic islet β-cells participates in glucose-stimulated insulin secretion and sarco(endo)plasmic reticulum ATPase (SERCA) inhibitor-induced apoptosis, and both are attenuated by pharmacologic or genetic reductions in iPLA(2)β activity and amplified by i...

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Detalhes bibliográficos
Main Authors: Song, Haowei, Wohltmann, Mary, Tan, Min, Bao, Shunzhong, Ladenson, Jack H., Turk, John
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285329/
https://ncbi.nlm.nih.gov/pubmed/22194610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.285114
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