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Preliminary Molecular Dynamic Simulations of the Estrogen Receptor Alpha Ligand Binding Domain from Antagonist to Apo

Estrogen receptors (ER) are known as nuclear receptors. They exist in the cytoplasm of human cells and serves as a DNA binding transcription factor that regulates gene expression. However the estrogen receptor also has additional functions independent of DNA binding. The human estrogen receptor come...

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Hlavní autoři: McGee, T. Dwight, Edwards, Jesse, Roitberg, Adrian E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Molecular Diversity Preservation International (MDPI) 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3662225/
https://ncbi.nlm.nih.gov/pubmed/18678925
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