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Preliminary Molecular Dynamic Simulations of the Estrogen Receptor Alpha Ligand Binding Domain from Antagonist to Apo

Estrogen receptors (ER) are known as nuclear receptors. They exist in the cytoplasm of human cells and serves as a DNA binding transcription factor that regulates gene expression. However the estrogen receptor also has additional functions independent of DNA binding. The human estrogen receptor come...

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書目詳細資料
Main Authors: McGee, T. Dwight, Edwards, Jesse, Roitberg, Adrian E.
格式: Artigo
語言:Inglês
出版: Molecular Diversity Preservation International (MDPI) 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3662225/
https://ncbi.nlm.nih.gov/pubmed/18678925
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