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The Effect of Antagonists on the Conformational Exchange of the Retinoid X Receptor Alpha Ligand-Binding Domain

The effect of retinoid X receptor (RXR) antagonists on the conformational exchange of the RXR ligand-binding domain (LBD) remains poorly characterized. To address this question, we used nuclear magnetic resonance spectroscopy to compare the chemical shift perturbations induced by RXR antagonists and...

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Detalhes bibliográficos
Main Authors: Lu, Jianyun, Dawson, Marcia I., Hu, Qiong Ying, Xia, Zebin, Dambacher, Jesse D., Ye, Mao, Zhang, Xiao-Kun, Li, Ellen
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436934/
https://ncbi.nlm.nih.gov/pubmed/19757405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mrc.2515
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