Anle138b: a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinson’s disease

In neurodegenerative diseases such as Alzheimer’s disease (AD), Parkinson’s disease (PD) and prion diseases, deposits of aggregated disease-specific proteins are found. Oligomeric aggregates are presumed to be the key neurotoxic agent. Here we describe the novel oligomer modulator anle138b [3-(1,3-b...

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Detalhes bibliográficos
Main Authors: Wagner, Jens, Ryazanov, Sergey, Leonov, Andrei, Levin, Johannes, Shi, Song, Schmidt, Felix, Prix, Catharina, Pan-Montojo, Francisco, Bertsch, Uwe, Mitteregger-Kretzschmar, Gerda, Geissen, Markus, Eiden, Martin, Leidel, Fabienne, Hirschberger, Thomas, Deeg, Andreas A., Krauth, Julian J., Zinth, Wolfgang, Tavan, Paul, Pilger, Jens, Zweckstetter, Markus, Frank, Tobias, Bähr, Mathias, Weishaupt, Jochen H., Uhr, Manfred, Urlaub, Henning, Teichmann, Ulrike, Samwer, Matthias, Bötzel, Kai, Groschup, Martin, Kretzschmar, Hans, Griesinger, Christian, Giese, Armin
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2013
Assuntos:
Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3661926/
https://ncbi.nlm.nih.gov/pubmed/23604588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-013-1114-9
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