Reducing tau aggregates with anle138b delays disease progression in a mouse model of tauopathies

Pathological tau aggregation leads to filamentous tau inclusions and characterizes neurodegenerative tauopathies such as Alzheimer’s disease and frontotemporal dementia and parkinsonism linked to chromosome 17. Tau aggregation coincides with clinical symptoms and is thought to mediate neurodegenerat...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol
Main Authors: Wagner, Jens, Krauss, Sybille, Shi, Song, Ryazanov, Sergey, Steffen, Julia, Miklitz, Carolin, Leonov, Andrei, Kleinknecht, Alexander, Göricke, Bettina, Weishaupt, Jochen H., Weckbecker, Daniel, Reiner, Anne M., Zinth, Wolfgang, Levin, Johannes, Ehninger, Dan, Remy, Stefan, Kretzschmar, Hans A., Griesinger, Christian, Giese, Armin, Fuhrmann, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2015
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4612332/
https://ncbi.nlm.nih.gov/pubmed/26439832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-015-1483-3
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