Anle138b: a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinson’s disease

In neurodegenerative diseases such as Alzheimer’s disease (AD), Parkinson’s disease (PD) and prion diseases, deposits of aggregated disease-specific proteins are found. Oligomeric aggregates are presumed to be the key neurotoxic agent. Here we describe the novel oligomer modulator anle138b [3-(1,3-b...

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主要な著者: Wagner, Jens, Ryazanov, Sergey, Leonov, Andrei, Levin, Johannes, Shi, Song, Schmidt, Felix, Prix, Catharina, Pan-Montojo, Francisco, Bertsch, Uwe, Mitteregger-Kretzschmar, Gerda, Geissen, Markus, Eiden, Martin, Leidel, Fabienne, Hirschberger, Thomas, Deeg, Andreas A., Krauth, Julian J., Zinth, Wolfgang, Tavan, Paul, Pilger, Jens, Zweckstetter, Markus, Frank, Tobias, Bähr, Mathias, Weishaupt, Jochen H., Uhr, Manfred, Urlaub, Henning, Teichmann, Ulrike, Samwer, Matthias, Bötzel, Kai, Groschup, Martin, Kretzschmar, Hans, Griesinger, Christian, Giese, Armin
フォーマット: Artigo
言語:Inglês
出版事項: Springer-Verlag 2013
主題:
Original Paper
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3661926/
https://ncbi.nlm.nih.gov/pubmed/23604588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-013-1114-9
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