Anle138b: a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinson’s disease

In neurodegenerative diseases such as Alzheimer’s disease (AD), Parkinson’s disease (PD) and prion diseases, deposits of aggregated disease-specific proteins are found. Oligomeric aggregates are presumed to be the key neurotoxic agent. Here we describe the novel oligomer modulator anle138b [3-(1,3-b...

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Hlavní autoři: Wagner, Jens, Ryazanov, Sergey, Leonov, Andrei, Levin, Johannes, Shi, Song, Schmidt, Felix, Prix, Catharina, Pan-Montojo, Francisco, Bertsch, Uwe, Mitteregger-Kretzschmar, Gerda, Geissen, Markus, Eiden, Martin, Leidel, Fabienne, Hirschberger, Thomas, Deeg, Andreas A., Krauth, Julian J., Zinth, Wolfgang, Tavan, Paul, Pilger, Jens, Zweckstetter, Markus, Frank, Tobias, Bähr, Mathias, Weishaupt, Jochen H., Uhr, Manfred, Urlaub, Henning, Teichmann, Ulrike, Samwer, Matthias, Bötzel, Kai, Groschup, Martin, Kretzschmar, Hans, Griesinger, Christian, Giese, Armin
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer-Verlag 2013
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Original Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3661926/
https://ncbi.nlm.nih.gov/pubmed/23604588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-013-1114-9
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