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Cocrystal structure of the ICAP1 PTB domain in complex with a KRIT1 peptide

Integrin cytoplasmic domain-associated protein-1 (ICAP1) is a suppressor of integrin activation and directly binds to the cytoplasmic tail of β1 integrins; its binding suppresses integrin activation by competition with talin. Krev/Rap1 interaction trapped-1 (KRIT1) releases ICAP1 suppression of inte...

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Detalhes bibliográficos
Main Authors: Liu, Weizhi, Boggon, Titus J.
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3660885/
https://ncbi.nlm.nih.gov/pubmed/23695561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309113010762
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