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Structural Determinants for Binding of Sorting Nexin 17 (SNX17) to the Cytoplasmic Adaptor Protein Krev Interaction Trapped 1 (KRIT1)

Sorting nexin 17 (SNX17) is a member of the family of cytoplasmic sorting nexin adaptor proteins that regulate endosomal trafficking of cell surface proteins. SNX17 localizes to early endosomes where it directly binds NPX(Y/F) motifs in the cytoplasmic tails of its target receptors to mediate their...

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Autors principals: Stiegler, Amy L., Zhang, Rong, Liu, Weizhi, Boggon, Titus J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4155697/
https://ncbi.nlm.nih.gov/pubmed/25059659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.584011
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