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Cocrystal structure of the ICAP1 PTB domain in complex with a KRIT1 peptide
Integrin cytoplasmic domain-associated protein-1 (ICAP1) is a suppressor of integrin activation and directly binds to the cytoplasmic tail of β1 integrins; its binding suppresses integrin activation by competition with talin. Krev/Rap1 interaction trapped-1 (KRIT1) releases ICAP1 suppression of inte...
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| Asıl Yazarlar: | , |
|---|---|
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
International Union of Crystallography
2013
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3660885/ https://ncbi.nlm.nih.gov/pubmed/23695561 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309113010762 |
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