PML-RARα co-operates with Sox4 in acute myeloid leukemia development in mice

Acute promyelocytic leukemia is characterized by a chromosomal translocation involving the retinoic acid receptor alpha gene. To identify co-operating pathways to leukemogenesis, we crossed MRP8-PML/RARA transgenic mice with BXH-2 mice which harbor an endogenous murine leukemia virus that causes acu...

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Main Authors: Omidvar, Nader, Maunakea, Mei Lin, Jones, Letetia, Sevcikova, Sabina, Yin, Bin, Himmel, Karen L., Tennant, Thelma R., Le Beau, Michelle M., Largaespada, David A., Kogan, Scott C.
Format: Artigo
Language:Inglês
Published: Ferrata Storti Foundation 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3659942/
https://ncbi.nlm.nih.gov/pubmed/23144197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2011.057067
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