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Disruption of forkhead transcription factor (FOXO) family members in mice reveals their functional diversification
Genetic analysis in Caenorhabditis elegans has uncovered essential roles for DAF-16 in longevity, metabolism, and reproduction. The mammalian orthologs of DAF-16, the closely-related FOXO subclass of forkhead transcription factors (FKHR/FOXO1, FKHRL1/FOXO3a, and AFX/FOXO4), also have important roles...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2004
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC365730/ https://ncbi.nlm.nih.gov/pubmed/14978268 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0400093101 |
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