Disruption of forkhead transcription factor (FOXO) family members in mice reveals their functional diversification

Genetic analysis in Caenorhabditis elegans has uncovered essential roles for DAF-16 in longevity, metabolism, and reproduction. The mammalian orthologs of DAF-16, the closely-related FOXO subclass of forkhead transcription factors (FKHR/FOXO1, FKHRL1/FOXO3a, and AFX/FOXO4), also have important roles...

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Autori principali: Hosaka, Taisuke, Biggs, William H., Tieu, David, Boyer, Antonia D., Varki, Nissi M., Cavenee, Webster K., Arden, Karen C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2004
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC365730/
https://ncbi.nlm.nih.gov/pubmed/14978268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0400093101
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