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PAX3-FOXO1 controls expression of the p57Kip2 cell-cycle regulator through degradation of EGR1
The chimeric protein PAX3-FOXO1, resulting from a translocation between chromosomes 2 and 13, is the most common genetic aberration in the alveolar subtype of the human skeletal muscle tumor, rhabdomyosarcoma. To understand how PAX3-FOXO1 contributes to tumor development, we isolated and characteriz...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2007
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2084300/ https://ncbi.nlm.nih.gov/pubmed/17986608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0708910104 |
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