Intersubunit signal transmission in integrins by a receptor-like interaction with a pull spring
The function of some multidomain proteins is regulated by interdomain communication. We use second-site suppressor cysteine mutations to test a hypothesis on how the inserted (I)-like domain in the integrin β-subunit regulates ligand binding by the neighboring I domain in the integrin α-subunit [Hut...
Kaydedildi:
| Yayımlandı: | Proc Natl Acad Sci U S A |
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| Asıl Yazarlar: | , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
National Academy of Sciences
2004
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC365718/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14978279/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0307340101 |
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