Intersubunit signal transmission in integrins by a receptor-like interaction with a pull spring
The function of some multidomain proteins is regulated by interdomain communication. We use second-site suppressor cysteine mutations to test a hypothesis on how the inserted (I)-like domain in the integrin β-subunit regulates ligand binding by the neighboring I domain in the integrin α-subunit [Hut...
Uloženo v:
| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2004
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC365718/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14978279/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0307340101 |
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