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Tumor Suppressor Protein p53 Negatively Regulates Human Pregnane X Receptor Activity
The human pregnane X receptor (PXR) regulates genes involved in drug metabolism and disposition. PXR associates with multiple corepressors that attenuate and coactivators that enhance its activity. PXR plays a vital role in the drug metabolism pathway, and a comprehensive examination of PXR-associat...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Pharmacology and Experimental Therapeutics
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3657101/ https://ncbi.nlm.nih.gov/pubmed/23536728 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.113.085092 |
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