Negative Regulation of the Tumor Suppressor p53 Gene by MicroRNAs

The tumor suppressor p53, encoded by the TP53 gene, is recognized as the guardian of the human genome because it regulates many downstream genes to exercise its function in cell cycle and cell death. Recent reports have revealed that several microRNAs (miRNAs) are important components of the p53 tum...

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Hauptverfasser: Kumar, Munish, Lu, Zhongxin, Takwi, Apana Agha L., Chen, Weiqun, Callander, Natalie S., Ramos, Kenneth S., Young, Ken H., Li, Yong
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3021102/
https://ncbi.nlm.nih.gov/pubmed/20935678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2010.457
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