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Negative Regulation of the Tumor Suppressor p53 Gene by MicroRNAs

The tumor suppressor p53, encoded by the TP53 gene, is recognized as the guardian of the human genome because it regulates many downstream genes to exercise its function in cell cycle and cell death. Recent reports have revealed that several microRNAs (miRNAs) are important components of the p53 tum...

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Main Authors: Kumar, Munish, Lu, Zhongxin, Takwi, Apana Agha L., Chen, Weiqun, Callander, Natalie S., Ramos, Kenneth S., Young, Ken H., Li, Yong
格式: Artigo
語言:Inglês
出版: 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3021102/
https://ncbi.nlm.nih.gov/pubmed/20935678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2010.457
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