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Regulation of p53-targeting microRNAs by polycyclic aromatic hydrocarbons: Implications in the etiology of multiple myeloma

Multiple myeloma (MM) is a common and deadly cancer of blood plasma cells. A unique feature of MM is the extremely low somatic mutation rate of the p53 tumor suppressor gene, in sharp contrast with about half of all human cancers where this gene is frequently mutated. Eleven miRNAs have been reporte...

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Dettagli Bibliografici
Pubblicato in:Mol Carcinog
Autori principali: Gordon, Michael W., Yan, Fang, Zhong, Xiaoming, Mazumder, Pranab Behari, Xu-Monette, Zijun Y., Young, Ken H., Ramos, Kenneth S., Li, Yong
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223015/
https://ncbi.nlm.nih.gov/pubmed/24798859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.22175
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