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Negative Regulation of Tumor Suppressor p53 by microRNA miR-504

Tumor suppressor p53 plays a central role in tumor prevention. p53 protein levels and activity are under a tight and complex regulation in cells to maintain the proper function of p53. microRNAs play a key role in the regulation of gene expression. Here we report the regulation of p53 through microR...

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Bibliographic Details
Main Authors: Hu, Wenwei, Chan, Chang S., Wu, Rui, Zhang, Cen, Sun, Yvonne, Song, Jun S., Tang, Laura H., Levine, Arnold J., Feng, Zhaohui
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900922/
https://ncbi.nlm.nih.gov/pubmed/20542001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.05.027
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