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Identification and Characterization of Phosphorylation Sites within the Pregnane X Receptor Protein

Pregnane X receptor (PXR) is a xenobiotic sensor regulating the expression of genes involved in xenobiotic detoxification and elimination. Phosphorylation plays an important role in modulating PXR activity and several phosphorylation sites have been predicted and characterized in in vitro experiment...

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Hlavní autoři: Elias, Ayesha, High, Anthony A., Mishra, Ashutosh, Ong, Su Sien, Wu, Jing, Peng, Junmin, Chen, Taosheng
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947193/
https://ncbi.nlm.nih.gov/pubmed/24184507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2013.10.015
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