Φορτώνει......
Serine 350 of Human Pregnane X Receptor Is Crucial for Its Heterodimerization with Retinoid X Receptor Alpha and Transactivation of Target Genes in Vitro and in Vivo
The human pregnane X receptor (hPXR), a member of the nuclear receptor superfamily, senses xenobiotics and controls the transcription of genes encoding drug-metabolizing enzymes and transporters. The regulation of hPXR’s transcriptional activation of its target genes is important for xenobiotic deto...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Biochem Pharmacol |
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| Κύριοι συγγραφείς: | , , , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2015
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4526351/ https://ncbi.nlm.nih.gov/pubmed/26119819 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2015.06.018 |
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