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Pregnane X Receptor and Cancer: Context-Specificity is Key

Pregnane X receptor (PXR) is an adopted orphan nuclear receptor that is activated by a wide-range of endobiotics and xenobiotics, including chemotherapy drugs. PXR plays a major role in the metabolism and clearance of xenobiotics and endobiotics in liver and intestine via induction of drug-metaboliz...

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Detalhes bibliográficos
Publicado no:Nucl Receptor Res
Main Authors: Pondugula, Satyanarayana R., Pavek, Petr, Mani, Sridhar
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5017004/
https://ncbi.nlm.nih.gov/pubmed/27617265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.11131/2016/101198
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