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Pregnane X Receptor and Cancer: Context-Specificity is Key
Pregnane X receptor (PXR) is an adopted orphan nuclear receptor that is activated by a wide-range of endobiotics and xenobiotics, including chemotherapy drugs. PXR plays a major role in the metabolism and clearance of xenobiotics and endobiotics in liver and intestine via induction of drug-metaboliz...
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| 發表在: | Nucl Receptor Res |
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| Main Authors: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5017004/ https://ncbi.nlm.nih.gov/pubmed/27617265 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.11131/2016/101198 |
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