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Pregnane xenobiotic receptor in cancer pathogenesis and therapeutic response
Pregnane xenobiotic receptor (PXR) is an orphan nuclear receptor that regulates the metabolism of endobiotics and xenobiotics. PXR is promiscuous and unique in that it is activated by a diverse group of xenochemicals, including therapeutic anticancer drugs and naturally-occurring endocrine disruptor...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3518034/ https://ncbi.nlm.nih.gov/pubmed/22939994 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2012.08.030 |
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