Imprint of evolution on protein structures
We attempt to understand the evolutionary origin of protein folds by simulating their divergent evolution with a three-dimensional lattice model. Starting from an initial seed lattice structure, evolution of model proteins progresses by sequence duplication and subsequent point mutations. A new gene...
Furkejuvvon:
| Publikašuvnnas: | Proc Natl Acad Sci U S A |
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| Váldodahkkit: | , , , |
| Materiálatiipa: | Artigo |
| Giella: | Inglês |
| Almmustuhtton: |
National Academy of Sciences
2004
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| Fáttát: | |
| Liŋkkat: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC365708/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14970345/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0306638101 |
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