Automated Synthesis of a Library of Triazolated 1,2,5-Thiadiazepane 1,1-Dioxides via a Double aza-Michael Strategy

The construction of a 96-member library of triazolated 1,2,5-thiadiazepane 1,1-dioxides was performed on a Chemspeed Accelerator (SLT-100) automated parallel synthesis platform, culminating in the successful preparation of 94 out of 96 possible products. The key step, a one-pot, sequential eliminati...

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Hlavní autoři: Zang, Qin, Javed, Salim, Hill, David, Ullah, Farman, Bi, Danse, Porubsky, Patrick, Neuenswander, Benjamin, Lushington, Gerald H., Santini, Conrad, Organ, Michael G., Hanson, Paul R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3656823/
https://ncbi.nlm.nih.gov/pubmed/22853708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/co300049u
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