Multicapillary Flow Reactor: Synthesis of 1,2,5-Thiadiazepane 1,1-Dioxide Library Utilizing One-Pot Elimination and Inter-/Intramolecular Double aza-Michael Addition Via Microwave-Assisted, Continuous-Flow Organic Synthesis (MACOS)

A microwave-assisted, continuous-flow organic synthesis (MACOS) protocol for the synthesis of functionalized 1,2,5-thiadiazepane 1,1-dioxide library, utilizing a one-pot elimination and inter-/intramolecular double aza-Michael addition strategy is reported. The optimized protocol in MACOS was utiliz...

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Detalhes bibliográficos
Main Authors: Ullah, Farman, Zang, Qin, Javed, Salim, Zhou, Aihua, Knudtson, Christopher A., Bi, Danse, Hanson, Paul R., Organ, Michael G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3827364/
https://ncbi.nlm.nih.gov/pubmed/24244871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1556/JFC-D-12-00015
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