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Synthesis of a Library of 1,5,2-Dithiazepine 1,1-Dioxides. Part 1: A One-Pot Sulfonylation/Thia-Michael Protocol

A novel one-pot sulfonylation/intramolecular thia-Michael protocol is reported for the synthesis of 1,5,2-dithiazepine 1,1-dioxides. Sulfonylation between cysteine ethyl ester/cysteamine and 2-chloroethanesulfonyl chloride, followed by in situ intramolecular thia-Michael addition, was achieved and a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zang, Qin, Zhou, Aihua, Javed, Salim, Maity, Pradip K., Knudtson, Chris A., Bi, Danse, Hastings, Jared J., Basha, Fatima Z., Hanson, Paul R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3873773/
https://ncbi.nlm.nih.gov/pubmed/24385679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3987/COM-12-S(N)121
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