Automated Synthesis of a 184-Member Library of Thiadiazepan-1, 1-dioxide-4-ones

[Image: see text] The construction of a 225-member (3 × 5 × 15) library of thiadiazepan-1,1-dioxide-4-ones was performed on a Chemspeed Accelerator (SLT-100) automated parallel synthesis platform, culminating in the successful preparation of 184/225 sultams. Three sultam core scaffolds were prepared...

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Autores principales: Fenster, Erik, Long, Toby R., Zang, Qin, Hill, David, Neuenswander, Benjamin, Lushington, Gerald H., Zhou, Aihua, Santini, Conrad, Hanson, Paul R.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3090501/
https://ncbi.nlm.nih.gov/pubmed/21309582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/co100060x
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