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SYMPHONY, an information-theoretic method for gene–gene and gene–environment interaction analysis of disease syndromes
We develop an information-theoretic method for gene–gene (GGI) and gene–environmental interactions (GEI) analysis of syndromes, defined as a phenotype vector comprising multiple quantitative traits (QTs). The K-way interaction information (KWII), an information-theoretic metric, was derived for mult...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3656633/ https://ncbi.nlm.nih.gov/pubmed/23423149 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/hdy.2012.123 |
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