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Comparison of information-theoretic to statistical methods for gene-gene interactions in the presence of genetic heterogeneity

BACKGROUND: Multifactorial diseases such as cancer and cardiovascular diseases are caused by the complex interplay between genes and environment. The detection of these interactions remains challenging due to computational limitations. Information theoretic approaches use computationally efficient d...

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Detalhes bibliográficos
Main Authors: Sucheston, Lara, Chanda, Pritam, Zhang, Aidong, Tritchler, David, Ramanathan, Murali
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996983/
https://ncbi.nlm.nih.gov/pubmed/20815886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-11-487
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