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AMBIENCE: A Novel Approach and Efficient Algorithm for Identifying Informative Genetic and Environmental Associations With Complex Phenotypes

We developed a computationally efficient algorithm AMBIENCE, for identifying the informative variables involved in gene–gene (GGI) and gene–environment interactions (GEI) that are associated with disease phenotypes. The AMBIENCE algorithm uses a novel information theoretic metric called phenotype-as...

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Detalhes bibliográficos
Main Authors: Chanda, Pritam, Sucheston, Lara, Zhang, Aidong, Brazeau, Daniel, Freudenheim, Jo L., Ambrosone, Christine, Ramanathan, Murali
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2567367/
https://ncbi.nlm.nih.gov/pubmed/18780753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.108.088542
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