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SYMPHONY, an information-theoretic method for gene–gene and gene–environment interaction analysis of disease syndromes

We develop an information-theoretic method for gene–gene (GGI) and gene–environmental interactions (GEI) analysis of syndromes, defined as a phenotype vector comprising multiple quantitative traits (QTs). The K-way interaction information (KWII), an information-theoretic metric, was derived for mult...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Knights, J, Yang, J, Chanda, P, Zhang, A, Ramanathan, M
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3656633/
https://ncbi.nlm.nih.gov/pubmed/23423149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/hdy.2012.123
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