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Apc regulates the function of hematopoietic stem cells largely through β-catenin–dependent mechanisms

Emerging evidence suggests that adenomatous polyposis coli (Apc) plays a critical role in the maintenance of hematopoietic stem/progenitor cells (HSCs/HPCs). The molecular pathways responsible for the function of Apc in HSCs/HPCs remain unclear. By genetic approach, we demonstrated that inactivation...

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Bibliografiske detaljer
Main Authors: Li, Wenshu, Hou, Yu, Ming, Ming, Yu, Long, Seba, Amber, Qian, Zhijian
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3656446/
https://ncbi.nlm.nih.gov/pubmed/23547052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-12-473470
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