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β-Catenin is a candidate therapeutic target for myeloid neoplasms with del(5q)

Deletion of the chromosome 5q [del(5q)] is one of the most common cytogenetic abnormalities observed in patients with de novo myelodysplastic syndromes (MDS) and therapy-related MDS or acute myeloid leukemia (t-MDS/tAML). Emerging evidence indicates that activation of the Wnt/β-catenin pathway contr...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Li, Liping, Sheng, Yue, Li, Wenshu, Hu, Chao, Mittal, Nupur, Tohyama, K, Seba, Amber, Zhao, You-Yang, Ozer, Howard, Zhu, Tongyu, Qian, Zhijian
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5559383/
https://ncbi.nlm.nih.gov/pubmed/28611040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-17-0202
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