DNA damage in normally and prematurely aged mice

Steady-state levels of spontaneous DNA damage, the by-product of normal metabolism and environmental exposure, are controlled by DNA repair pathways. Incomplete repair or an age-related increase in damage production and/or decline in repair could lead to an accumulation of DNA damage, increasing mut...

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Huvudupphovsmän: Maslov, Alexander Y., Ganapathi, Shireen, Westerhof, Maaike, Quispe, Wilber, White, Ryan R., Van Houten, Bennett, Reiling, Erwin, Dollé, Martijn E.T., van Steeg, Harry, Hasty, Paul, Hoeijmakers, Jan H.J., Vijg, Jan
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3655155/
https://ncbi.nlm.nih.gov/pubmed/23496256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12071
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