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High-throughput sequencing in mutation detection: a new generation of genotoxicity tests?

The advent of next generation sequencing (NGS) technology has provided the means to directly analyze the genetic material in primary cells or tissues of any species in a high throughput manner for mutagenic effects of potential genotoxic agents. In principle, direct, genome-wide sequencing of human...

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Detaylı Bibliyografya
Yayımlandı:Mutat Res
Asıl Yazarlar: Maslov, Alexander Y., Quispe-Tintaya, Wilber, Gorbacheva, Tatyana, White, Ryan R., Vijg, Jan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4532622/
https://ncbi.nlm.nih.gov/pubmed/25934519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrfmmm.2015.03.014
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