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High-throughput sequencing in mutation detection: a new generation of genotoxicity tests?
The advent of next generation sequencing (NGS) technology has provided the means to directly analyze the genetic material in primary cells or tissues of any species in a high throughput manner for mutagenic effects of potential genotoxic agents. In principle, direct, genome-wide sequencing of human...
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| Publicado en: | Mutat Res |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4532622/ https://ncbi.nlm.nih.gov/pubmed/25934519 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrfmmm.2015.03.014 |
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