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High-throughput sequencing in mutation detection: a new generation of genotoxicity tests?

The advent of next generation sequencing (NGS) technology has provided the means to directly analyze the genetic material in primary cells or tissues of any species in a high throughput manner for mutagenic effects of potential genotoxic agents. In principle, direct, genome-wide sequencing of human...

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Dettagli Bibliografici
Pubblicato in:Mutat Res
Autori principali: Maslov, Alexander Y., Quispe-Tintaya, Wilber, Gorbacheva, Tatyana, White, Ryan R., Vijg, Jan
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4532622/
https://ncbi.nlm.nih.gov/pubmed/25934519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrfmmm.2015.03.014
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