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Genome Dynamics in Aging Mice

Random spontaneous genome rearrangements are difficult to detect in vivo, especially in postmitotic tissues. Using a lacZ-plasmid reporter mouse model, we have previously presented evidence for the accumulation of large genome rearrangements in various tissues, including postmitotic tissues, during...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Dollé, Martijn E.T., Vijg, Jan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2002
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC187544/
https://ncbi.nlm.nih.gov/pubmed/12421760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.125502
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