MeCP2 binds to 5hmc enriched within active genes and accessible chromatin in the nervous system
The high level of 5-hydroxymethylcytosine (5hmC) present in neuronal genomes suggests that mechanisms interpreting 5hmC in the central nervous system (CNS) may differ from those present in embryonic stem cells. Here we present quantitative, genome-wide analysis of 5hmC, 5-methylcytosine (5mC) and ge...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3653293/ https://ncbi.nlm.nih.gov/pubmed/23260135 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.11.022 |
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