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MeCP2 binds to 5hmc enriched within active genes and accessible chromatin in the nervous system

The high level of 5-hydroxymethylcytosine (5hmC) present in neuronal genomes suggests that mechanisms interpreting 5hmC in the central nervous system (CNS) may differ from those present in embryonic stem cells. Here we present quantitative, genome-wide analysis of 5hmC, 5-methylcytosine (5mC) and ge...

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書誌詳細
主要な著者: Mellen, Marian, Ayata, Pinar, Dewell, Scott, Kriaucionis, Skirmantas, Heintz, Nathaniel
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3653293/
https://ncbi.nlm.nih.gov/pubmed/23260135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.11.022
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