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The nuclear DNA base, 5-hydroxymethylcytosine is present in brain and enriched in Purkinje neurons

Despite of the importance of epigenetic regulation in neurological disorders, little is known about neuronal chromatin. Cerebellar Purkinje neurons have large and euchromatic nuclei, whilst granule cell nuclei are small and have a more typical heterochromatin distribution. While comparing the abunda...

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Detalhes bibliográficos
Main Authors: Kriaucionis, Skirmantas, Heintz, Nathaniel
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3263819/
https://ncbi.nlm.nih.gov/pubmed/19372393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1169786
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