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The nuclear DNA base, 5-hydroxymethylcytosine is present in brain and enriched in Purkinje neurons

Despite of the importance of epigenetic regulation in neurological disorders, little is known about neuronal chromatin. Cerebellar Purkinje neurons have large and euchromatic nuclei, whilst granule cell nuclei are small and have a more typical heterochromatin distribution. While comparing the abunda...

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Sonraí Bibleagrafaíochta
Main Authors: Kriaucionis, Skirmantas, Heintz, Nathaniel
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2009
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3263819/
https://ncbi.nlm.nih.gov/pubmed/19372393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1169786
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