Llwytho...
5-hydroxymethylcytosine marks regions with reduced mutation frequency in human DNA
CpG dinucleotides are the main mutational hot-spot in most cancers. The characteristic elevated C>T mutation rate in CpG sites has been related to 5-methylcytosine (5mC), an epigenetically modified base which resides in CpGs and plays a role in transcription silencing. In brain nearly a third of...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | eLife |
|---|---|
| Prif Awduron: | , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
eLife Sciences Publications, Ltd
2016
|
| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4931910/ https://ncbi.nlm.nih.gov/pubmed/27183007 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.17082 |
| Tagiau: |
Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!
|