5-hydroxymethylcytosine marks promoters in colon that resist DNA hypermethylation in cancer

BACKGROUND: The discovery of cytosine hydroxymethylation (5hmC) as a mechanism that potentially controls DNA methylation changes typical of neoplasia prompted us to investigate its behaviour in colon cancer. 5hmC is globally reduced in proliferating cells such as colon tumours and the gut crypt prog...

詳細記述

保存先:
書誌詳細
出版年:Genome Biol
主要な著者: Uribe-Lewis, Santiago, Stark, Rory, Carroll, Thomas, Dunning, Mark J, Bachman, Martin, Ito, Yoko, Stojic, Lovorka, Halim, Silvia, Vowler, Sarah L, Lynch, Andy G, Delatte, Benjamin, de Bony, Eric J, Colin, Laurence, Defrance, Matthieu, Krueger, Felix, Silva, Ana-Luisa, ten Hoopen, Rogier, Ibrahim, Ashraf EK, Fuks, François, Murrell, Adele
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2015
主題:
Research
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4380107/
https://ncbi.nlm.nih.gov/pubmed/25853800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-015-0605-5
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!

類似資料