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MeCP2 nuclear dynamics in live neurons results from low and high affinity chromatin interactions
Methyl-CpG-binding-Protein 2 (MeCP2) is an abundant nuclear protein highly enriched in neurons. Here we report live-cell single-molecule imaging studies of the kinetic features of mouse MeCP2 at high spatial-temporal resolution. MeCP2 displays dynamic features that are distinct from both highly mobi...
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| Gepubliceerd in: | eLife |
|---|---|
| Hoofdauteurs: | , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
eLife Sciences Publications, Ltd
2019
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6957317/ https://ncbi.nlm.nih.gov/pubmed/31868585 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.51449 |
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