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SUMOylation of the Farnesoid X Receptor (FXR) Regulates the Expression of FXR Target Genes
The farnesoid X receptor (FXR) belongs to a family of ligand-activated transcription factors that regulate many aspects of metabolism including bile acid homeostasis. Here we show that FXR is covalently modified by the small ubiquitin-like modifier (Sumo1), an important regulator of cell signaling a...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3650421/ https://ncbi.nlm.nih.gov/pubmed/23546875 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.443937 |
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