Farnesoid X receptor (FXR): Structures and ligands

Farnesoid X receptor (FXR) is a bile acid activated nuclear receptor (BAR) and is mainly expressed in the liver and intestine. Upon ligand binding, FXR regulates key genes involved in the metabolic process of bile acid synthesis, transport and reabsorption and is also involved in the metabolism of c...

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Dades bibliogràfiques
Publicat a:Comput Struct Biotechnol J
Autors principals: Jiang, Longying, Zhang, Huajun, Xiao, Desheng, Wei, Hudie, Chen, Yongheng
Format: Artigo
Idioma:Inglês
Publicat: Research Network of Computational and Structural Biotechnology 2021
Matèries:
Review
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8091178/
https://ncbi.nlm.nih.gov/pubmed/33995909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2021.04.029
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