Farnesoid X receptor (FXR): Structures and ligands

Farnesoid X receptor (FXR) is a bile acid activated nuclear receptor (BAR) and is mainly expressed in the liver and intestine. Upon ligand binding, FXR regulates key genes involved in the metabolic process of bile acid synthesis, transport and reabsorption and is also involved in the metabolism of c...

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Bibliografische gegevens
Gepubliceerd in:Comput Struct Biotechnol J
Hoofdauteurs: Jiang, Longying, Zhang, Huajun, Xiao, Desheng, Wei, Hudie, Chen, Yongheng
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Research Network of Computational and Structural Biotechnology 2021
Onderwerpen:
Review
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8091178/
https://ncbi.nlm.nih.gov/pubmed/33995909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2021.04.029
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