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Farnesoid X receptor (FXR): Structures and ligands

Farnesoid X receptor (FXR) is a bile acid activated nuclear receptor (BAR) and is mainly expressed in the liver and intestine. Upon ligand binding, FXR regulates key genes involved in the metabolic process of bile acid synthesis, transport and reabsorption and is also involved in the metabolism of c...

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Detalhes bibliográficos
Publicado no:Comput Struct Biotechnol J
Main Authors: Jiang, Longying, Zhang, Huajun, Xiao, Desheng, Wei, Hudie, Chen, Yongheng
Formato: Artigo
Idioma:Inglês
Publicado em: Research Network of Computational and Structural Biotechnology 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8091178/
https://ncbi.nlm.nih.gov/pubmed/33995909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2021.04.029
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