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Farnesoid X receptor (FXR): Structures and ligands
Farnesoid X receptor (FXR) is a bile acid activated nuclear receptor (BAR) and is mainly expressed in the liver and intestine. Upon ligand binding, FXR regulates key genes involved in the metabolic process of bile acid synthesis, transport and reabsorption and is also involved in the metabolism of c...
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| 發表在: | Comput Struct Biotechnol J |
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| Main Authors: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Research Network of Computational and Structural Biotechnology
2021
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8091178/ https://ncbi.nlm.nih.gov/pubmed/33995909 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2021.04.029 |
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