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Farnesoid X receptor (FXR): Structures and ligands

Farnesoid X receptor (FXR) is a bile acid activated nuclear receptor (BAR) and is mainly expressed in the liver and intestine. Upon ligand binding, FXR regulates key genes involved in the metabolic process of bile acid synthesis, transport and reabsorption and is also involved in the metabolism of c...

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Podrobná bibliografie
Vydáno v:Comput Struct Biotechnol J
Hlavní autoři: Jiang, Longying, Zhang, Huajun, Xiao, Desheng, Wei, Hudie, Chen, Yongheng
Médium: Artigo
Jazyk:Inglês
Vydáno: Research Network of Computational and Structural Biotechnology 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8091178/
https://ncbi.nlm.nih.gov/pubmed/33995909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2021.04.029
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