Structure- and Modeling-based Identification of the Adenovirus E4orf4 Binding Site in the Protein Phosphatase 2A B55α Subunit

The adenovirus E4orf4 protein regulates the progression of viral infection and when expressed outside the context of the virus it induces nonclassical, cancer cell-specific apoptosis. All E4orf4 functions known to date require an interaction between E4orf4 and protein phosphatase 2A (PP2A), which is...

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Hlavní autoři: Horowitz, Ben, Sharf, Rakefet, Avital-Shacham, Meirav, Pechkovsky, Antonina, Kleinberger, Tamar
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2013
Témata:
Computational Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3650409/
https://ncbi.nlm.nih.gov/pubmed/23530045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.343756
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